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Tregs utilize β-galactoside-binding protein to transiently inhibit PI3K/p21(ras) activity of human CD8(+) T cells to block their TCR-mediated ERK activity and proliferation
Regulatory T cells (Tregs) and beta-galactoside-binding protein (βGBP), a regulatory protein often found expressed at sites of immunological privilege, have similar functions. Their presence affects the outcome of harmful autoimmunity and cancers, including experimental autoimmune encephalomyelitis...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2752359/ https://ncbi.nlm.nih.gov/pubmed/19520156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2009.06.003 |
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