Tregs utilize β-galactoside-binding protein to transiently inhibit PI3K/p21(ras) activity of human CD8(+) T cells to block their TCR-mediated ERK activity and proliferation

Regulatory T cells (Tregs) and beta-galactoside-binding protein (βGBP), a regulatory protein often found expressed at sites of immunological privilege, have similar functions. Their presence affects the outcome of harmful autoimmunity and cancers, including experimental autoimmune encephalomyelitis...

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Bibliografiska uppgifter
Huvudupphovsmän: Baatar, Dolgor, Olkhanud, Purevdorj B., Wells, Valerie, Indig, Fred E., Mallucci, Livio, Biragyn, Arya
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752359/
https://ncbi.nlm.nih.gov/pubmed/19520156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2009.06.003
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