Pro-inflammatory cytokines and HIV-1 synergistically enhance CXCL10 expression in human astrocytes

HIV encephalitis (HIVE), the pathologic correlate of HIV-associated dementia (HAD) is characterized by astrogliosis, cytokine/chemokine dysregulation and neuronal degeneration. Increasing evidence suggests that inflammation is actively involved in the pathogenesis of HAD. In fact, the severity of HA...

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Main Authors: Williams, Rachel, Dhillon, Navneet K., Hegde, Sonia T., Yao, Honghong, Peng, Fuwang, Callen, Shannon, Chebloune, Yahia, Davis, Randall L., Buch, Shilpa J.
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667210/
https://ncbi.nlm.nih.gov/pubmed/18985732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.20801
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