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Genetic variants in frizzled-related protein (FRZB) and the risk of colorectal neoplasia

OBJECTIVE: The Wnt/APC/β-catenin signaling pathway, which includes frizzled-related protein (FRZB), plays a critical role in the development of colorectal cancer, and recent evidence suggests that the functional polymorphism, FRZB Arg324Gly, may be associated with risk for this disease. To determine...

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Detalhes bibliográficos
Main Authors: Berndt, Sonja I., Huang, Wen-Yi, Yeager, Meredith, Weissfeld, Joel L., Chanock, Stephen J., Hayes, Richard B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667207/
https://ncbi.nlm.nih.gov/pubmed/19067193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10552-008-9274-y
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