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The zinc fingers of the SR-like protein ZRANB2 are single-stranded RNA-binding domains that recognize 5′ splice site-like sequences

The alternative splicing of mRNA is a critical process in higher eukaryotes that generates substantial proteomic diversity. Many of the proteins that are essential to this process contain arginine/serine-rich (RS) domains. ZRANB2 is a widely-expressed and highly-conserved RS-domain protein that can...

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Detalhes bibliográficos
Main Authors: Loughlin, Fionna E., Mansfield, Robyn E., Vaz, Paula M., McGrath, Aaron P., Setiyaputra, Surya, Gamsjaeger, Roland, Chen, Eva S., Morris, Brian J., Guss, J. Mitchell, Mackay, Joel P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667063/
https://ncbi.nlm.nih.gov/pubmed/19304800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802466106
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