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The mismatch repair system promotes DNA polymerase ζ-dependent translesion synthesis in yeast

DNA lesions that block replication can be bypassed by error-prone or error-free mechanisms. Error-prone mechanisms rely on specialized translesion synthesis (TLS) DNA polymerases that directly replicate over the lesion, whereas error-free pathways use an undamaged duplex as a template for lesion byp...

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Autores principales: Lehner, Kevin, Jinks-Robertson, Sue
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667058/
https://ncbi.nlm.nih.gov/pubmed/19307574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812715106
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