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Blocking of Proteolytic Processing and Deletion of Glycosaminoglycan Side Chain of Mouse DMP1 by Substituting Critical Amino Acid Residues

Dentin matrix protein 1 (DMP1) is present in the extracellular matrix (ECM) of dentin and bone as processed NH(2)- and COOH-terminal fragments, resulting from proteolytic cleavage at the NH(2) termini of 4 aspartic acid residues during rat DMP1 processing. One cleavage site residue, Asp(181) (corres...

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Autors principals: Peng, Tao, Huang, Bingzhen, Sun, Yao, Lu, Yongbo, Bonewald, Lynda, Chen, Shuo, Butler, William T., Feng, Jerry Q., D'Souza, Rena N., Qin, Chunlin
Format: Artigo
Idioma:Inglês
Publicat: S. Karger AG 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666981/
https://ncbi.nlm.nih.gov/pubmed/18698130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000151373
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