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Studies of the DMP1 57-kDa Functional Domain both in vivo and in vitro

Dmp1-null mice and patients with mutations in dentin matrix protein 1 (DMP1) resulting in autosomal recessive hypophosphatemic rickets display similar skeletal defects. As mutations were observed in the last 18 amino acids of DMP1 in 1 subset of patients and as fragments of intact DMP1, a 37-kDa N-t...

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Main Authors: Lu, Yongbo, Qin, Chunlin, Xie, Yixia, Bonewald, Lynda F., Feng, Jian Q.
Format: Artigo
Jezik:Inglês
Izdano: S. Karger AG 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667139/
https://ncbi.nlm.nih.gov/pubmed/18728349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000151727
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