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USP17 Regulates Ras Activation and Cell Proliferation by Blocking RCE1 Activity
The proto-oncogene Ras undergoes a series of post-translational modifications at its carboxyl-terminal CAAX motif that are essential for its proper membrane localization and function. One step in this process is the cleavage of the CAAX motif by the enzyme Ras-converting enzyme 1 (RCE1). Here we sho...
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| Autors principals: | , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2666611/ https://ncbi.nlm.nih.gov/pubmed/19188362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807216200 |
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