The Insulin Receptor Substrate of 53 kDa (IRSp53) Limits Hippocampal Synaptic Plasticity

IRSp53 is an essential intermediate between the activation of Rac and Cdc42 GTPases and the formation of cellular protrusions; it affects cell shape by coupling membrane-deforming activity with the actin cytoskeleton. IRSp53 is highly expressed in neurons where it is also an abundant component of th...

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Detalhes bibliográficos
Main Authors: Sawallisch, Corinna, Berhörster, Kerstin, Disanza, Andrea, Mantoani, Sara, Kintscher, Michael, Stoenica, Luminita, Dityatev, Alexander, Sieber, Sabrina, Kindler, Stefan, Morellini, Fabio, Schweizer, Michaela, Boeckers, Tobias M., Korte, Martin, Scita, Giorgio, Kreienkamp, Hans-Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666575/
https://ncbi.nlm.nih.gov/pubmed/19208628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808425200
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