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Depletion of the Poly(C)-binding Proteins αCP1 and αCP2 from K562 Cells Leads to p53-independent Induction of Cyclin-dependent Kinase Inhibitor (CDKN1A) and G(1) Arrest

The α-globin poly(C)-binding proteins (αCPs) comprise an abundant and widely expressed set of K-homolog domain RNA-binding proteins. αCPs regulate the expression of a number of cellular and viral mRNAs at the levels of splicing, stability, and translation. Previous surveys have identified 160 mRNAs...

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Autors principals: Waggoner, Shelly A., Johannes, Gregg J., Liebhaber, Stephen A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666552/
https://ncbi.nlm.nih.gov/pubmed/19211566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806986200
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