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The Fixation Probability of Rare Mutators in Finite Asexual Populations

A mutator is an allele that increases the mutation rate throughout the genome by disrupting some aspect of DNA replication or repair. Mutators that increase the mutation rate by the order of 100-fold have been observed to spontaneously emerge and achieve high frequencies in natural populations and i...

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Hlavní autoři: Wylie, C. Scott, Ghim, Cheol-Min, Kessler, David, Levine, Herbert
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666523/
https://ncbi.nlm.nih.gov/pubmed/19153261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.094532
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