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The Fixation Probability of Rare Mutators in Finite Asexual Populations

A mutator is an allele that increases the mutation rate throughout the genome by disrupting some aspect of DNA replication or repair. Mutators that increase the mutation rate by the order of 100-fold have been observed to spontaneously emerge and achieve high frequencies in natural populations and i...

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Autors principals: Wylie, C. Scott, Ghim, Cheol-Min, Kessler, David, Levine, Herbert
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666523/
https://ncbi.nlm.nih.gov/pubmed/19153261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.094532
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