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Stereocontrolled Alkylative Construction of Quaternary Carbon Centers

[Image: see text] Protocols for the stereodefined formation of α,α-disubstituted enolates of pseudoephedrine amides are presented followed by the implementation of these in diastereoselective alkylation reactions. Direct alkylation of α,α-disubstituted pseudoephedrine amide substrates is demonstrate...

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Autori principali: Kummer, David A., Chain, William J., Morales, Marvin R., Quiroga, Olga, Myers, Andrew G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666470/
https://ncbi.nlm.nih.gov/pubmed/18788739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja806021y
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