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Molecular and Phenotypic Characterisation of Paediatric Glioma Cell Lines as Models for Preclinical Drug Development

BACKGROUND: Although paediatric high grade gliomas resemble their adult counterparts in many ways, there appear to be distinct clinical and biological differences. One important factor hampering the development of new targeted therapies is the relative lack of cell lines derived from childhood gliom...

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Detalhes bibliográficos
Main Authors: Bax, Dorine A., Little, Suzanne E., Gaspar, Nathalie, Perryman, Lara, Marshall, Lynley, Viana-Pereira, Marta, Jones, Tania A., Williams, Richard D., Grigoriadis, Anita, Vassal, Gilles, Workman, Paul, Sheer, Denise, Reis, Rui M., Pearson, Andrew D. J., Hargrave, Darren, Jones, Chris
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666263/
https://ncbi.nlm.nih.gov/pubmed/19365568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005209
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