LCAT synthesized by primary astrocytes esterifies cholesterol on glia-derived lipoproteins

Lipid trafficking in the brain is essential for the maintenance and repair of neuronal membranes, especially after neurotoxic insults. However, brain lipid metabolism is not completely understood. In plasma, LCAT catalyses the esterification of free cholesterol on circulating lipoproteins, a key ste...

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Hauptverfasser: Hirsch-Reinshagen, Veronica, Donkin, James, Stukas, Sophie, Chan, Jennifer, Wilkinson, Anna, Fan, Jianjia, Parks, John S., Kuivenhoven, Jan Albert, Lütjohann, Dieter, Pritchard, Haydn, Wellington, Cheryl L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2009
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666175/
https://ncbi.nlm.nih.gov/pubmed/19065001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M800584-JLR200
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