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Interferon-alpha inhibits glucocorticoid receptor-mediated gene transcription via STAT5 activation in mouse HT22 cells

Interferon (IFN)-alpha is an innate immune cytokine that induces significant depressive symptoms in clinical populations. A number of mechanisms have been considered regarding the relationship between IFN-alpha and depression, including the effects of IFN-alpha on the hypothalamic-pituitary-adrenal...

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Autori principali: Hu, Fang, Pace, Thaddeus W.W., Miller, Andrew H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666112/
https://ncbi.nlm.nih.gov/pubmed/19167480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2009.01.001
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