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The oncogenic LIM-only transcription factor Lmo2 regulates angiogenesis but not vasculogenesis in mice

The LMO2 gene is activated by chromosomal translocations in human T cell acute leukemias, but in mouse embryogenesis, Lmo2 is essential for initiation of yolk sac and definitive hematopoiesis. The LMO2 protein comprises two LIM–zinc-finger-like protein interaction modules and functions by interactio...

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發表在:Proc Natl Acad Sci U S A
Principais autores: Yamada, Yoshihiro, Pannell, Richard, Forster, Alan, Rabbitts, Terence H.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2000
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在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26661/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10618416/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.1.320
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