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Tandem LIM domain-containing proteins, LIMK1 and LMO1, directly bind to force-bearing keratin intermediate filaments

Summary: The cytoskeleton of the cell is constantly exposed to physical forces that regulate cellular functions. Selected members of the LIM (Lin-11, Isl-1, and Mec-3) domain-containing protein family accumulate along force-bearing actin fibers, with evidence supporting that the LIM domain is solely...

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Autori principali: Dah Som Kim, Joleen S. Cheah, Tzu Wei Lai, Karen X. Zhao, Skylar R. Foust, Yuh-Ru Julie Lee, Su Hao Lo, Volkmar Heinrich, Soichiro Yamada
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2024-07-01
Serie:Cell Reports
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Accesso online:http://www.sciencedirect.com/science/article/pii/S221112472400809X
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