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Precursor-product discrimination by La protein during tRNA metabolism
La proteins bind pre-tRNAs at their UUU-3'OH ends, facilitating their maturation. While the mechanism by which La binds pre-tRNA 3' trailers is known, the function of the RNA-binding β-sheet surface of RRM1 is unknown. How La dissociates from UUU-3'OH-containing trailers after 3'...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2666094/ https://ncbi.nlm.nih.gov/pubmed/19287396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1573 |
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