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Rho Kinase Inhibition Improves Endothelial Function in Human Subjects With Coronary Artery Disease

Investigations from basic biology suggest that activation of the Rho/Rho kinase pathway reduces the bioavailability of nitric oxide (NO) and thereby promotes atherosclerosis and its clinical complications. Yet, little information is available about the relationship of the Rho/Rho kinase pathway to N...

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Detalhes bibliográficos
Main Authors: Nohria, Anju, Grunert, Matthew E., Rikitake, Yoshiyuki, Noma, Kensuke, Prsic, Adnan, Ganz, Peter, Liao, James K., Creager, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666070/
https://ncbi.nlm.nih.gov/pubmed/17095725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.RES.0000251668.39526.c7
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