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A combination of proteasome inhibitors and antibiotics prevents lethality in a septic shock model
Our recent studies with lactacystin, a prototype proteasome inhibitor, have suggested that the proteasome is a key regulator of LPS-induced signaling pathways contributing to the inflammatory process. Moreover, lactacystin protects animals from LPS-induced shock. Therefore, we sought to identify oth...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2666041/ https://ncbi.nlm.nih.gov/pubmed/18809656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1753425908096855 |
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