Signalling of the BCR is regulated by a lipid rafts-localised transcription factor, Bright

Regulation of BCR signalling strength is crucial for B-cell development and function. Bright is a B-cell-restricted factor that complexes with Bruton's tyrosine kinase (Btk) and its substrate, transcription initiation factor-I (TFII-I), to activate immunoglobulin heavy chain gene transcription...

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Autori principali: Schmidt, Christian, Kim, Dongkyoon, Ippolito, Gregory C, Naqvi, Hassan R, Probst, Loren, Mathur, Shawn, Rosas-Acosta, German, Wilson, Van G, Oldham, Athenia L, Poenie, Martin, Webb, Carol F, Tucker, Philip W
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666038/
https://ncbi.nlm.nih.gov/pubmed/19214191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.20
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