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Signalling of the BCR is regulated by a lipid rafts-localised transcription factor, Bright
Regulation of BCR signalling strength is crucial for B-cell development and function. Bright is a B-cell-restricted factor that complexes with Bruton's tyrosine kinase (Btk) and its substrate, transcription initiation factor-I (TFII-I), to activate immunoglobulin heavy chain gene transcription...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2666038/ https://ncbi.nlm.nih.gov/pubmed/19214191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.20 |
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