Characterization of a novel intraocular drug delivery system using crystalline lipid antiviral prodrugs of ganciclovir and cyclic cidofovir

PURPOSE: We have previously reported a novel intraocular drug delivery system using hexadecyloxypropyl-phospho-ganciclovir (HDP-P-GCV) as a prototype. We hypothesized that many biologically effective compounds could be modified to crystalline lipid prodrugs and be delivered directly into the vitreou...

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Autors principals: Cheng, Lingyun, Hostetler, Karl Y., Lee, Jeffery, Koh, Hyoung Jun, James, Beadle, R., Bessho, Kenichiro, Toyoguchi, Mitsuko, Aldern, Kathy, Bovet, Jean-Marc, Freeman, William R.
Format: Artigo
Idioma:Inglês
Publicat: 2004
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666013/
https://ncbi.nlm.nih.gov/pubmed/15505067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.04-0064
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