Evaluation of High-Resolution Melting Analysis as a Diagnostic Tool to Detect the BRAF V600E Mutation in Colorectal Tumors

BRAF V600E is the predominantly occurring mutation of the cytoplasmic kinase BRAF, and, in colorectal cancer, its determination provides a diagnostic exclusion criterion for hereditary nonpolyposis colorectal cancer. The aim of our study was to develop a sensitive BRAF V600E high resolution melting...

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Detalhes bibliográficos
Main Authors: Pichler, Martin, Balic, Marija, Stadelmeyer, Elke, Ausch, Christoph, Wild, Martina, Guelly, Christian, Bauernhofer, Thomas, Samonigg, Hellmut, Hoefler, Gerald, Dandachi, Nadia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665863/
https://ncbi.nlm.nih.gov/pubmed/19213871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2009.080100
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