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Multiple whole-genome alignments without a reference organism

Multiple sequence alignments have become one of the most commonly used resources in genomics research. Most algorithms for multiple alignment of whole genomes rely either on a reference genome, against which all of the other sequences are laid out, or require a one-to-one mapping between the nucleot...

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Autors principals: Dubchak, Inna, Poliakov, Alexander, Kislyuk, Andrey, Brudno, Michael
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665786/
https://ncbi.nlm.nih.gov/pubmed/19176791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.081778.108
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