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The functional importance of telomere clustering: Global changes in gene expression result from SIR factor dispersion
Budding yeast telomeres and cryptic mating-type loci are enriched at the nuclear envelope, forming foci that sequester silent information regulators (SIR factors), much as heterochromatic chromocenters in higher eukaryotes sequester HP1. Here we examine the impact of such subcompartments for regulat...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2665780/ https://ncbi.nlm.nih.gov/pubmed/19179643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.083881.108 |
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