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The functional importance of telomere clustering: Global changes in gene expression result from SIR factor dispersion

Budding yeast telomeres and cryptic mating-type loci are enriched at the nuclear envelope, forming foci that sequester silent information regulators (SIR factors), much as heterochromatic chromocenters in higher eukaryotes sequester HP1. Here we examine the impact of such subcompartments for regulat...

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Detalhes bibliográficos
Main Authors: Taddei, Angela, Van Houwe, Griet, Nagai, Shigeki, Erb, Ionas, van Nimwegen, Erik, Gasser, Susan M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665780/
https://ncbi.nlm.nih.gov/pubmed/19179643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.083881.108
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