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Diverse cis factors controlling Alu retrotransposition: What causes Alu elements to die?

The human genome contains nearly 1.1 million Alu elements comprising roughly 11% of its total DNA content. Alu elements use a copy and paste retrotransposition mechanism that can result in de novo disease insertion alleles. There are nearly 900,000 old Alu elements from subfamilies S and J that appe...

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Auteurs principaux: Comeaux, Matthew S., Roy-Engel, Astrid M., Hedges, Dale J., Deininger, Prescott L.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665774/
https://ncbi.nlm.nih.gov/pubmed/19273617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.089789.108
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