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Alu elements: An intrinsic source of human genome instability

Alu elements are ~300 bp sequences that have amplified via an RNA intermediate leading to the accumulation of over 1 million copies in the human genome. Although few of the copies are active, Alu germline activity is the highest of all human retrotransposons and does significantly contribute to gene...

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Detalhes bibliográficos
Main Authors: Ade, Catherine, Roy-Engel, Astrid M., Deininger, Prescott L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982648/
https://ncbi.nlm.nih.gov/pubmed/24080407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coviro.2013.09.002
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