Antibody Discovery via Multiplexed Single Cell Characterization

The secreted immunoglobulin footprint of single hybridoma cells, containing ~10 fg of antibody purified in situ, has been probed for 9 properties concurrently by use of detection labels comprising 280 nm combinatorially colored fluorescent latex beads functionalized with proteins. Specificity of eac...

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Detalhes bibliográficos
Main Authors: Harriman, William D., Collarini, Ellen J., Sperinde, Gizette V., Strandh, Magnus, Fatholahi, Marjan M., Dutta, April, Lee, Yunji, Mettler, Shelley E., Keyt, Bruce A., Ellsworth, Stote L., Kauvar, Lawrence M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665128/
https://ncbi.nlm.nih.gov/pubmed/19087879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2008.11.009
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