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Synaptotagmin 2 Couples Mucin Granule Exocytosis to Ca(2+) Signaling from Endoplasmic Reticulum
Synaptotagmin 2 (Syt2) functions as a low affinity, fast exocytic Ca(2+) sensor in neurons, where it is activated by Ca(2+) influx through voltage-gated channels. Targeted insertion of lacZ into the mouse syt2 locus reveals expression in mucin-secreting goblet cells of the airways. In these cells, r...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2665099/ https://ncbi.nlm.nih.gov/pubmed/19208631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807849200 |
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