Posttranslational Protein Modifications in Type 1 Diabetes - Genetic Studies with PCMT1, the Repair Enzyme Protein Isoaspartate Methyltransferase (PIMT) Encoding Gene

BACKGROUND: Posttranslational protein modifications have been implicated in the development of autoimmunity. Protein L-isoaspartate (D-aspartate) O-methyltransferase (PIMT) repairs modified proteins and is encoded by PCMT1, located in a region linked to type 1 diabetes (T1D), namely IDDM5. AIM: To e...

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Hlavní autoři: Wägner, Ana M., Cloos, Paul, Bergholdt, Regine, Eising, Stefanie, Brorsson, Caroline, Stalhut, Martin, Christgau, Stephan, Nerup, Jørn, Pociot, Flemming
Médium: Artigo
Jazyk:Inglês
Vydáno: SBDR - Society for Biomedical Diabetes Research 2008
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Original Data
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664675/
https://ncbi.nlm.nih.gov/pubmed/19290383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1900/RDS.2008.5.225
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