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A Common Single Nucleotide Polymorphism Alters the Synthesis and Secretion of Neuropeptide Y

A single nucleotide polymorphism (SNP) in the neuropeptide Y gene has been associated with elevated serum lipid levels and cardiovascular disease. The polymorphism (T1128C) changes the seventh amino acid in the prohormone from leucine to proline. It has been speculated this alters neuropeptide Y (NP...

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Autori principali: Mitchell, Gregory C., Wang, Qian, Ramamoorthy, Prabhu, Whim, Matthew D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664626/
https://ncbi.nlm.nih.gov/pubmed/19118176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0343-08.2008
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