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A Common Single Nucleotide Polymorphism Alters the Synthesis and Secretion of Neuropeptide Y

A single nucleotide polymorphism (SNP) in the neuropeptide Y gene has been associated with elevated serum lipid levels and cardiovascular disease. The polymorphism (T1128C) changes the seventh amino acid in the prohormone from leucine to proline. It has been speculated this alters neuropeptide Y (NP...

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Hlavní autoři: Mitchell, Gregory C., Wang, Qian, Ramamoorthy, Prabhu, Whim, Matthew D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664626/
https://ncbi.nlm.nih.gov/pubmed/19118176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0343-08.2008
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