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Phosphorylation of the Neurospora clock protein FREQUENCY determines its degradation rate and strongly influences the period length of the circadian clock

Under free running conditions, FREQUENCY (FRQ) protein, a central component of the Neurospora circadian clock, is progressively phosphorylated, becoming highly phosphorylated before its degradation late in the circadian day. To understand the biological function of FRQ phosphorylation, kinase inhibi...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Liu, Yi, Loros, Jennifer, Dunlap, Jay C.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2000
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Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26646/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10618401/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.1.234
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