Phosphorylation of the Neurospora clock protein FREQUENCY determines its degradation rate and strongly influences the period length of the circadian clock

Under free running conditions, FREQUENCY (FRQ) protein, a central component of the Neurospora circadian clock, is progressively phosphorylated, becoming highly phosphorylated before its degradation late in the circadian day. To understand the biological function of FRQ phosphorylation, kinase inhibi...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Liu, Yi, Loros, Jennifer, Dunlap, Jay C.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2000
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26646/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10618401/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.1.234
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