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MET Pathway as a Therapeutic Target
Dysregulation of MET receptor tyrosine kinase pathway leads to cell proliferation, protection from apoptosis, angiogenesis, invasion and metastasis. It can be dysregulated via overexpression, constitutive activation, gene amplification, ligand-dependent activation or mutation. New drugs targeting va...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2664527/ https://ncbi.nlm.nih.gov/pubmed/19333071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e31819d6f91 |
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