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Quantitative exploration of the catalytic landscape separating divergent plant sesquiterpene synthases
Throughout molecular evolution, organisms create assorted chemicals in response to varying ecological niches. Catalytic landscapes underlie metabolic evolution, wherein mutational steps alter the biosynthetic properties of enzymes. We report the first systematic quantitative characterization of a ca...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2664519/ https://ncbi.nlm.nih.gov/pubmed/18776889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.113 |
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