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Reversal of learning deficits in a Tsc2(+/−) mouse model of tuberous sclerosis
Tuberous sclerosis is a single-gene disorder caused by heterozygous mutations in the TSC1 (9q34) or TSC2 (16p13.3) gene1,2 and is frequently associated with mental retardation, autism and epilepsy. Even individuals with tuberous sclerosis and a normal intelligence quotient (approximately 50%)3–5 are...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2664098/ https://ncbi.nlm.nih.gov/pubmed/18568033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1788 |
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