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A mouse model for nonsyndromic deafness (DFNB12) links hearing loss to defects in tip links of mechanosensory hair cells

Deafness is the most common form of sensory impairment in humans and is frequently caused by single gene mutations. Interestingly, different mutations in a gene can cause syndromic and nonsyndromic forms of deafness, as well as progressive and age-related hearing loss. We provide here an explanation...

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Detalhes bibliográficos
Main Authors: Schwander, Martin, Xiong, Wei, Tokita, Joshua, Lelli, Andrea, Elledge, Heather M., Kazmierczak, Piotr, Sczaniecka, Anna, Kolatkar, Anand, Wiltshire, Tim, Kuhn, Peter, Holt, Jeffrey R., Kachar, Bechara, Tarantino, Lisa, Müller, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664065/
https://ncbi.nlm.nih.gov/pubmed/19270079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900691106
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