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Dynamics of Telomeres and Promyelocytic Leukemia Nuclear Bodies in a Telomerase-negative Human Cell Line

Telomerase-negative tumor cells maintain their telomeres via an alternative lengthening of telomeres (ALT) mechanism. This process involves the association of telomeres with promyelocytic leukemia nuclear bodies (PML-NBs). Here, the mobility of both telomeres and PML-NBs as well as their interaction...

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Autores principales: Jegou, Thibaud, Chung, Inn, Heuvelman, Gerrit, Wachsmuth, Malte, Görisch, Sabine M., Greulich-Bode, Karin M., Boukamp, Petra, Lichter, Peter, Rippe, Karsten
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663922/
https://ncbi.nlm.nih.gov/pubmed/19211845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-02-0108
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