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Tetraspanin Proteins Regulate Membrane Type-1 Matrix Metalloproteinase-dependent Pericellular Proteolysis

Membrane type-1 matrix metalloproteinase (MT1-MMP) supports tumor cell invasion through extracellular matrix barriers containing fibrin, collagen, fibronectin, and other proteins. Here, we show that simultaneous knockdown of two or three members of the tetraspanin family (CD9, CD81, and TSPAN12) mar...

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Autors principals: Lafleur, Marc A., Xu, Daosong, Hemler, Martin E.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663921/
https://ncbi.nlm.nih.gov/pubmed/19211836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-11-1149
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