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Neuronal survival and resistance to HIV-1 Tat toxicity in the primary culture of rat fetal neurons
In this study we report that primary cultures of rat fetal neurons contain subpopulations of cells that may be sensitive or resistant to HIV-1 Tat neurotoxicity. We demonstrate that rapid binding/uptake of Tat 1–86 for 2 hours was sufficient to trigger caspase activation and neurodegeneration in rat...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2663805/ https://ncbi.nlm.nih.gov/pubmed/19013459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2008.10.006 |
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