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Different effects of selective dopamine uptake inhibitors, GBR 12909 and WIN 35428 on HIV-1 Tat toxicity in rat fetal midbrain neurons

Drug abuse is a risk factor for neurological complications in HIV infection. Cocaine has been shown to exacerbate HIV-associated brain pathology and enhance neurotoxicity of HIV-1 Tat and gp120 proteins. In this study, we found that the selective inhibitor of dopamine transporter (DAT) function, 1-[...

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Autori principali: Aksenov, Michael Y., Aksenova, Marina V., Silvers, Janelle M., Mactutus, Charles F., Booze, Rosemarie M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205582/
https://ncbi.nlm.nih.gov/pubmed/18606182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2008.06.003
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