Development of New Lipid-Based Paclitaxel Nanoparticles Using Sequential Simplex Optimization

The objective of these studies was to develop Cremophor-free lipid-based paclitaxel (PX) nanoparticle formulations prepared from warm microemulsion precursors. To identify and optimize new nanoparticles, experimental design was performed combining Taguchi array and sequential simplex optimization. T...

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Bibliographic Details
Main Authors: Dong, Xiaowei, Mattingly, Cynthia A., Tseng, Michael, Cho, Moo, Adams, Val R., Mumper, Russell J.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663602/
https://ncbi.nlm.nih.gov/pubmed/19111929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejpb.2008.11.012
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