Development of Idarubicin and Doxorubicin Solid Lipid Nanoparticles to Overcome Pgp–mediated Multiple Drug Resistance in Leukemia

The objectives of these studies were to investigate and compare solid lipid nanoparticles (SLNs) of two anthracyclines, idarubicin (IDA) and doxorubicin (DOX), against Pgp-mediated multiple drug resistance (MDR.) in-vitro and in-vivo using different human and murine cancer cell models. IDA and DOX S...

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Detalhes bibliográficos
Main Authors: Ma, Ping, Dong, Xiaowei, Swadley, Courtney L., Gupte, Anshul, Leggas, Markos, Ledebur, Harry C., Mumper, Russell J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805476/
https://ncbi.nlm.nih.gov/pubmed/20055093
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