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Polygenic Threshold Model with Sex Dimorphism in Clubfoot Inheritance: The Carter Effect

Background: Idiopathic clubfoot is approximately twice as common in males than in females. The reason for this discrepancy is unclear but may represent an inherent difference in the susceptibility to the deformity. If this difference is due to genetic factors it is predicted that in order to inherit...

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Autors principals: Kruse, Lisa M., Dobbs, Matthew B., Gurnett, Christina A.
Format: Artigo
Idioma:Inglês
Publicat: Journal of Bone and Joint Surgery, Inc 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663333/
https://ncbi.nlm.nih.gov/pubmed/19047715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2106/JBJS.G.01346
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