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Polygenic Threshold Model with Sex Dimorphism in Clubfoot Inheritance: The Carter Effect

Background: Idiopathic clubfoot is approximately twice as common in males than in females. The reason for this discrepancy is unclear but may represent an inherent difference in the susceptibility to the deformity. If this difference is due to genetic factors it is predicted that in order to inherit...

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Detalhes bibliográficos
Main Authors: Kruse, Lisa M., Dobbs, Matthew B., Gurnett, Christina A.
Formato: Artigo
Idioma:Inglês
Publicado em: Journal of Bone and Joint Surgery, Inc 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663333/
https://ncbi.nlm.nih.gov/pubmed/19047715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2106/JBJS.G.01346
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