Foot-and-Mouth Disease Virus Can Induce a Specific and Rapid CD4(+) T-Cell-Independent Neutralizing and Isotype Class-Switched Antibody Response in Naïve Cattle

The role of T-lymphocyte subsets in recovery from foot-and-mouth disease virus (FMDV) infection in calves was investigated by administering subset-specific monoclonal antibodies. The depletion of circulating CD4(+) or WC1(+) γδ T cells was achieved for a period extending from before challenge to aft...

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Autores principales: Juleff, Nicholas, Windsor, Miriam, Lefevre, Eric A., Gubbins, Simon, Hamblin, Pip, Reid, Elizabeth, McLaughlin, Kerry, Beverley, Peter C. L., Morrison, Ivan W., Charleston, Bryan
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663275/
https://ncbi.nlm.nih.gov/pubmed/19176618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02613-08
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