Bovine Plasmacytoid Dendritic Cells Are the Major Source of Type I Interferon in Response to Foot-and-Mouth Disease Virus In Vitro and In Vivo

Type I interferons (alpha/beta interferons [IFN-α/β]) are the main innate cytokines that are able to induce a cellular antiviral state, thereby limiting viral replication and disease pathology. Plasmacytoid dendritic cells (pDCs) play a crucial role in the control of viral infections, especially in...

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Détails bibliographiques
Auteurs principaux: Reid, Elizabeth, Juleff, Nicholas, Gubbins, Simon, Prentice, Helen, Seago, Julian, Charleston, Bryan
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2011
Sujets:
Pathogenesis and Immunity
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126242/
https://ncbi.nlm.nih.gov/pubmed/21307187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02495-10
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